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Retrovirus-Associated Heparan Sulfate Mediates Immobilization and Gene Transfer on Recombinant Fibronectin

Recombinant retroviruses have been shown to bind to fibronectin (FN) and increase the efficiency of gene transfer to a variety of cell types. Despite recent work to optimize gene transfer on recombinant FN, the mechanism of retrovirus binding to FN and the interactions of target cells with the bound...

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Autori principali: Lei, Pedro, Bajaj, Bharat, Andreadis, Stelios T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136998/
https://ncbi.nlm.nih.gov/pubmed/12163592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.17.8722-8728.2002
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