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In vivo selection of lethal mutations reveals two functional domains in arginyl-tRNA synthetase.

Using random mutagenesis and a genetic screening in yeast, we isolated 26 mutations that inactivate Saccharomyces cerevisiae arginyl-tRNA synthetase (ArgRS). The mutations were identified and the kinetic parameters of the corresponding proteins were tested after purification of the expression produc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Geslain, R, Martin, F, Delagoutte, B, Cavarelli, J, Gangloff, J, Eriani, G
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369925/
https://ncbi.nlm.nih.gov/pubmed/10744027
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