Base pairing with U6atac snRNA is required for 5' splice site activation of U12-dependent introns in vivo.

The minor U12-dependent class of eukaryotic nuclear pre-mRNA introns is spliced by a distinct spliceosomal mechanism that requires the function of U11, U12, U5, U4atac, and U6atac snRNAs. Previous work has shown that U11 snRNA plays a role similar to U1 snRNA in the major class spliceosome by base p...

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Bibliographic Details
Main Authors: Incorvaia, R, Padgett, R A
Format: Artigo
Language:Inglês
Published: 1998
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369652/
https://ncbi.nlm.nih.gov/pubmed/9622129
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