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The U14 snoRNA is required for 2'-O-methylation of the pre-18S rRNA in Xenopus oocytes.

We have studied the role of the U14 small nucleolar RNA (snoRNA) in pre-rRNA methylation and processing in Xenopus oocytes. Depletion of U14 in Xenopus oocytes was achieved by co-injecting two nonoverlapping antisense oligonucleotides. Focusing on the earliest precursor, depletion experiments reveal...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Dunbar, D A, Baserga, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369608/
https://ncbi.nlm.nih.gov/pubmed/9570319
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