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Neurogenin3 is differentially required for endocrine cell fate specification in the intestinal and gastric epithelium

Endocrine cells of the pancreas and the gastrointestinal tract derive from multipotent endodermal stem cells. We have shown previously that the basic helix– loop–helix (bHLH) transcription factor neurogenin3 (ngn3) is required for the specification of the endocrine lineage in uncommitted progenitors...

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Udgivet i:EMBO J
Principais autores: Jenny, Marjorie, Uhl, Céline, Roche, Colette, Duluc, Isabelle, Guillermin, Valérie, Guillemot, Francois, Jensen, Jan, Kedinger, Michèle, Gradwohl, Gérard
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2002
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Articles
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136953/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12456641/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf649
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