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Mutant Human Cytomegalovirus Lacking the Immediate-Early TRS1 Coding Region Exhibits a Late Defect

The human cytomegalovirus IRS1 and TRS1 open reading frames encode immediate-early proteins with identical N-terminal domains and divergent C-terminal regions. Both proteins have been shown previously to activate reporter genes in transfection assays in cooperation with other viral gene products. We...

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Autori principali: Blankenship, Catherine A., Shenk, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136912/
https://ncbi.nlm.nih.gov/pubmed/12414969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.12290-12299.2002
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