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Assembly of an active translation initiation factor complex by a viral protein

Recruitment of the 40S ribosome to the 5′ end of a eukaryotic mRNA requires assembly of translation initiation factors eIF4E, the cap-binding protein, together with eIF4A and eIF4G into a complex termed eIF4F. While the translational repressor 4E-BP1 regulates binding of eIF4E to eIF4G, the forces r...

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Bibliografiske detaljer
Main Authors: Walsh, Derek, Mohr, Ian
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369048/
https://ncbi.nlm.nih.gov/pubmed/16481474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1375006
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