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Pausing during Reverse Transcription Increases the Rate of Retroviral Recombination
Retroviruses package two copies of genomic RNA into viral particles. During the minus-sense DNA synthesis step of reverse transcription, the nascent DNA can transfer multiple times between the two copies of the genome, resulting in recombination. The mechanism for this process is similar to the proc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1369041/ https://ncbi.nlm.nih.gov/pubmed/16474155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.5.2483-2494.2006 |
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