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Isoflurane depresses hippocampal CA1 glutamate nerve terminals without inhibiting fiber volleys

BACKGROUND: Anesthetic-induced CNS depression is thought to involve reduction of glutamate release from nerve terminals. Recent studies suggest that isoflurane reduces glutamate release by block of Na channels. To further investigate this question we examined the actions of isoflurane, TTX, extracel...

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Detalhes bibliográficos
Main Authors: Winegar, Bruce D, MacIver, M Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1369004/
https://ncbi.nlm.nih.gov/pubmed/16409641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-7-5
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