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Characterization of RNA Determinants Recognized by the Arginine- and Proline-Rich Region of Us11, a Herpes Simplex Virus Type 1-Encoded Double-Stranded RNA Binding Protein That Prevents PKR Activation

The herpes simplex virus Us11 gene product inhibits activation of the cellular PKR kinase and associates with a limited number of unrelated viral and cellular RNA molecules via a carboxyl-terminal 68-amino-acid segment rich in arginine and proline. To characterize the determinants underlying the rec...

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Autori principali: Khoo, David, Perez, Cesar, Mohr, Ian
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136894/
https://ncbi.nlm.nih.gov/pubmed/12414939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.23.11971-11981.2002
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