Cell Cycle Arrest by Human Cytomegalovirus 86-kDa IE2 Protein Resembles Premature Senescence

Primary human embryo lung fibroblasts and adult diploid fibroblasts infected by the human cytomegalovirus (HCMV) display β-galactosidase (β-Gal) activity at neutral pH (senescence-associated β-Gal [SA-β-Gal] activity) and overexpression of the plasminogen activator inhibitor type 1 (PAI-1) gene, two...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Noris, Emanuela, Zannetti, Claudia, Demurtas, Anna, Sinclair, John, De Andrea, Marco, Gariglio, Marisa, Landolfo, Santo
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12414954/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.23.12135-12148.2002
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