A dose-ranging study of UK-68,798, a novel class III anti-arrhythmic agent, in normal volunteers.

1. UK-68,798, a novel class III anti-arrhythmic agent was administered intravenously to twelve healthy volunteers in a placebo controlled, double-blind, dose-escalating study. 2. Doses of 5 and 10 micrograms kg-1 of UK-68,798 selectively and significantly prolonged the QT interval, with mean maximum...

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Detalhes bibliográficos
Main Authors: Gemmill, J D, Howie, C A, Meredith, P A, Kelman, A W, Rasmussen, H S, Hillis, W S, Elliott, H L
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368601/
https://ncbi.nlm.nih.gov/pubmed/1958435
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