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Mefloquine pharmacokinetics and resistance in children with acute falciparum malaria.

The pharmacokinetic properties of mefloquine hydrochloride (15 mg base kg -1) were studied in 12 Karen children (five girls, seven boys) aged between 5 and 10 years presenting with uncomplicated falciparum malaria. The drug was well tolerated. Mean (s.d.) peak blood drug concentrations of 2031 (831)...

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Bibliographische Detailangaben
Hauptverfasser: Nosten, F, ter Kuile, F, Chongsuphajaisiddhi, T, Na Bangchang, K, Karbwang, J, White, N J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368477/
https://ncbi.nlm.nih.gov/pubmed/1888626
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