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Metabolism of the aldose reductase inhibitor ALO1567 in man.

1. The metabolism of the aldose reductase inhibitor, ALO1567, was studied in man. The major biotransformation pathway was aromatic hydroxylation followed by glucuronide conjugation. 2. Hydroxylation occurred at several positions on the fluorene ring. The major metabolite was identified as the 7-hydr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Y H, Hudson, J E, Barker, R C, York, B M, Brazzell, R K
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368447/
https://ncbi.nlm.nih.gov/pubmed/1931471
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