A method of studying pharmacokinetics in man at picomolar drug concentrations.

1. We describe a new method that enables the tissue kinetics of picomolar concentrations of drugs to be measured in man. The method is based on the administration of a drug, labelled with a short-lived positron-emitting radioisotope, such as carbon-11 (t1/2 = 20.4 min, beta + = 99.8%) or fluorine-18...

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Dettagli Bibliografici
Autori principali: Cunningham, V J, Pike, V W, Bailey, D, Freemantle, C A, Page, B C, Jones, A K, Kensett, M J, Bateman, D, Luthra, S K, Jones, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368439/
https://ncbi.nlm.nih.gov/pubmed/1931467
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