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Metabolism of almitrine in extensive and poor metabolisers of debrisoquine/sparteine.

1. Almitrine bismesylate displays wide inter-subject variation in peak plasma concentrations and can induce peripheral polyneuropathy. 2. The phenotyped volunteer panel approach was used to examine whether almitrine oxidation displayed a genetic polymorphism of the debrisoquine/sparteine type. 3. Th...

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Bibliografiske detaljer
Main Authors: Herchuelz, A, Gangji, D, Derenne, F, Jeanniot, J P, Douchamps, J
Format: Artigo
Sprog:Inglês
Udgivet: 1991
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368414/
https://ncbi.nlm.nih.gov/pubmed/2015173
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