Distribution of Chemokine Receptor CCR2 and CCR5 Genotypes and Their Relative Contribution to Human Immunodeficiency Virus Type 1 (HIV-1) Seroconversion, Early HIV-1 RNA Concentration in Plasma, and Later Disease Progression

At the CC (β) chemokine receptor 2 (CCR2) and CCR5 loci, combinations of common single-nucleotide polymorphisms (SNPs) and a 32-bp deletion (Δ32) form nine stable haplotypes (designated A through G*2). The distribution of these CCR2-CCR5 haplotypes was examined among 703 participants in the Multicen...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Tang, Jianming, Shelton, Brent, Makhatadze, Nina J., Zhang, Yuting, Schaen, Margaret, Louie, Leslie G., Goedert, James J., Seaberg, Eric C., Margolick, Joseph B., Mellors, John, Kaslow, Richard A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Pathogenesis and Immunity
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11752157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.2.662-672.2002
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