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Lack of effect of co-trimoxazole on the pharmacokinetics and pharmacodynamics of nifedipine.

The pharmacokinetics of nifedipine and its primary oxidised metabolite, M-I were studied in nine healthy volunteers following a single oral dose of 20 mg nifedipine alone or after pretreatment with oral co-trimoxazole. Following pretreatment with co-trimoxazole, no significant effect was detected on...

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Detalhes bibliográficos
Main Authors: Edwards, C, Monkman, S, Cholerton, S, Rawlins, M D, Idle, J R, Ferner, R E
Formato: Artigo
Idioma:Inglês
Publicado em: 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368311/
https://ncbi.nlm.nih.gov/pubmed/2288835
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