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An evaluation of the alpha-adrenoceptor antagonism produced by SK&F 86466 in healthy normotensive males.

SK&F 86466 is a novel, potent alpha-adrenoceptor antagonist which, in animal experiments, is reported to show a high selectivity for alpha 2-adrenoceptors at both pre- and post-junctional sites. The effects of two intravenous doses of 80 and 200 micrograms kg-1 of SK&F 86466 were assessed in...

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Autors principals: Schafers, R F, Elliott, H L, Howie, C A, Reid, J L
Format: Artigo
Idioma:Inglês
Publicat: 1990
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368310/
https://ncbi.nlm.nih.gov/pubmed/1981137
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