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The 2-Kilobase Intron of the Herpes Simplex Virus Type 1 Latency-Associated Transcript Has a Half-Life of Approximately 24 Hours in SY5Y and COS-1 Cells

The herpes simplex virus type 1 (HSV-1) 2-kb latency-associated transcript (LAT) is a stable intron, which accumulates in cells both lytically and latently infected with HSV-1. We have used a tetracycline-repressible expression system to determine the half-life of the 2-kb LAT RNA intron in the huma...

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Detalhes bibliográficos
Main Authors: Thomas, Darby L., Lock, Martin, Zabolotny, Janice M., Mohan, Bangalore R., Fraser, Nigel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136830/
https://ncbi.nlm.nih.gov/pubmed/11752144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.532-540.2002
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