Fractionated ifosfamide therapy produces a time-dependent increase in ifosfamide metabolism.

1. Fifteen patients received 1.5 g m-2 of ifosfamide intravenously over 0.5 h every day for 5 days. Twenty-one courses of treatment were studied. Plasma was assayed for ifosfamide by gas liquid chromatography and plasma alkylating activity was measured using the nitrobenzylpyridine (NBP) reaction. 2...

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Hlavní autoři: Lewis, L D, Fitzgerald, D L, Harper, P G, Rogers, H J
Médium: Artigo
Jazyk:Inglês
Vydáno: 1990
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368173/
https://ncbi.nlm.nih.gov/pubmed/2271371
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