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Different desensitization mechanisms of two α(1)-adrenoceptor subtypes in the contraction of rabbit aorta

Using α(1)-adrenoceptor selective antagonists chlorethylclonidine (CEC) and WB4101, both functional and radioligand binding studies showed that rabbit aorta contains at least two pharmacologically distinct α(1)-adrenoceptor subtypes of approximately 10% α(1a) and 90% α(1b) receptors, and that each r...

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Detalles Bibliográficos
Main Authors: Suzuki, E., Tsujimoto, G., Hashimoto, K.
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1368111/
https://ncbi.nlm.nih.gov/pubmed/1980076
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