Systemic, Mucosal, and Heterotypic Immune Induction in Mice Inoculated with Venezuelan Equine Encephalitis Replicons Expressing Norwalk Virus-Like Particles

Norwalk-like viruses (NLVs) are a diverse group of single-stranded, nonenveloped, positive-polarity RNA viruses and are the leading cause of epidemic acute gastroenteritis in the United States. In this study, the major capsid gene of Norwalk virus, the prototype NLV, has been cloned and expressed in...

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Главные авторы: Harrington, Patrick R., Yount, Boyd, Johnston, Robert E., Davis, Nancy, Moe, Christine, Baric, Ralph S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2002
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC136807/
https://ncbi.nlm.nih.gov/pubmed/11752163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.2.730-742.2002
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