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Truncated Forms of Glycoprotein D of Herpes Simplex Virus 1 Capable of Blocking Apoptosis and of Low-Efficiency Entry into Cells Form a Heterodimer Dependent on the Presence of a Cysteine Located in the Shared Transmembrane Domains

Earlier studies have shown that herpes simplex virus 1 (HSV-1) virions of mutant lacking glycoprotein D (gD) and made in either complementing (gD(−/+) stocks) or noncomplementing cells (gD(−/−) stocks) induce apoptosis. Subsequent studies have shown that apoptosis induced by gD(−/−) mutant virus sto...

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Autori principali: Zhou, Guoying, Roizman, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC136777/
https://ncbi.nlm.nih.gov/pubmed/12388708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11469-11475.2002
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