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Modeling the VPAC(2)-Activated cAMP/PKA Signaling Pathway: From Receptor to Circadian Clock Gene Induction

Increasing evidence suggests an important role for VPAC(2)-activated signal transduction pathways in maintaining a synchronized biological clock in the suprachiasmatic nucleus (SCN). Activation of the VPAC(2) signaling pathway induces per1 gene expression in the SCN and phase-shifts the circadian cl...

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Detalhes bibliográficos
Main Authors: Hao, Haiping, Zak, Daniel E., Sauter, Thomas, Schwaber, James, Ogunnaike, Babatunde A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367307/
https://ncbi.nlm.nih.gov/pubmed/16339878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065250
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