The Bacteriophage T4 Inhibitor and Coactivator AsiA Inhibits Escherichia coli RNA Polymerase More Rapidly in the Absence of σ(70) Region 1.1: Evidence that Region 1.1 Stabilizes the Interaction between σ(70) and Core

The N-terminal region (region 1.1) of σ(70), the primary σ subunit of Escherichia coli RNA polymerase, is a negatively charged domain that affects the DNA binding properties of σ(70) regions 2 and 4. Region 1.1 prevents the interaction of free σ(70) with DNA and modulates the formation of stable (op...

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Detalhes bibliográficos
Main Authors: Hinton, Deborah M., Vuthoori, Srilatha, Mulamba, Rebecca
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Gene Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367253/
https://ncbi.nlm.nih.gov/pubmed/16452409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.188.4.1279-1285.2006
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