ICP27 Interacts with the RNA Export Factor Aly/REF To Direct Herpes Simplex Virus Type 1 Intronless mRNAs to the TAP Export Pathway

Herpes simplex virus type 1 (HSV-1) protein ICP27 facilitates the export of viral intronless mRNAs. ICP27 shuttles between the nucleus and cytoplasm, which has been shown to require a leucine-rich nuclear export sequence (NES). ICP27 export was reported to be sensitive to the CRM1 inhibitor leptomyc...

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Detalhes bibliográficos
Main Authors: Chen, I-Hsiung Brandon, Sciabica, Kathryn S., Sandri-Goldin, Rozanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136725/
https://ncbi.nlm.nih.gov/pubmed/12438613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12877-12889.2002
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