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cdc2/Cyclin B1-Dependent Phosphorylation of EBNA2 at Ser243 Regulates Its Function in Mitosis

Epstein-Barr virus (EBV) nuclear antigen 2 (EBNA2) transactivates EBV genes in latently infected B cells. We have shown that mitotic hyperphosphorylation of EBNA2 suppresses its ability to transactivate the latent membrane protein 1 (LMP1) promoter. In this follow-up study, we identify EBNA2 Ser243...

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Autors principals: Yue, Wei, Shackelford, Julia, Pagano, Joseph S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367142/
https://ncbi.nlm.nih.gov/pubmed/16439560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.2045-2050.2006
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