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Regulation of Cardiac Sarcoplasmic Reticulum Ca Release by Luminal [Ca] and Altered Gating Assessed with a Mathematical Model

Cardiac excitation-contraction coupling is initialized by the release of Ca from the sarcoplasmic reticulum (SR) in response to a sudden increase in local cytosolic [Ca] ([Ca](i)) within the junctional cleft. We have tested the hypothesis that functional ryanodine receptor (RyR) regulation plays a m...

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Bibliografiska uppgifter
Huvudupphovsmän: Shannon, Thomas R., Wang, Fei, Bers, Donald M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2005
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366975/
https://ncbi.nlm.nih.gov/pubmed/16169970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068734
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