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Regulation of Cardiac Sarcoplasmic Reticulum Ca Release by Luminal [Ca] and Altered Gating Assessed with a Mathematical Model
Cardiac excitation-contraction coupling is initialized by the release of Ca from the sarcoplasmic reticulum (SR) in response to a sudden increase in local cytosolic [Ca] ([Ca](i)) within the junctional cleft. We have tested the hypothesis that functional ryanodine receptor (RyR) regulation plays a m...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366975/ https://ncbi.nlm.nih.gov/pubmed/16169970 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.068734 |
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