Comparative Vaccine Studies in HLA-A2.1-Transgenic Mice Reveal a Clustered Organization of Epitopes Presented in Hepatitis C Virus Natural Infection

A polyepitopic CD8(+)-T-cell response is thought to be critical for control of hepatitis C virus (HCV) infection. Using transgenic mice, we analyzed the immunogenicity and dominance of most known HLA-A2.1 epitopes presented during infection by using vaccines that carry the potential to enter clinica...

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Detalhes bibliográficos
Main Authors: Himoudi, Nourredine, Abraham, Jean-Daniel, Fournillier, Anne, Lone, Yu Chun, Joubert, Aurélie, De Beeck, Anne Op, Freida, Delphine, Lemonnier, François, Kieny, Marie Paule, Inchauspé, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136695/
https://ncbi.nlm.nih.gov/pubmed/12438599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.12735-12746.2002
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