Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Modeling and simulation of the calcium signaling events that precede long-term depression of synaptic activity in cerebellar Purkinje cells are performed using the Virtual Cell biological modeling framework. It is found that the unusually high density and low sensitivity of inositol-1,4,5-trisphosph...

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Detalhes bibliográficos
Main Authors: Hernjak, Nicholas, Slepchenko, Boris M., Fernald, Kathleen, Fink, Charles C., Fortin, Dale, Moraru, Ion I., Watras, James, Loew, Leslie M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Biophysical Theory and Modeling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366947/
https://ncbi.nlm.nih.gov/pubmed/16169982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065771
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