Modeling and Analysis of Calcium Signaling Events Leading to Long-Term Depression in Cerebellar Purkinje Cells

Modeling and simulation of the calcium signaling events that precede long-term depression of synaptic activity in cerebellar Purkinje cells are performed using the Virtual Cell biological modeling framework. It is found that the unusually high density and low sensitivity of inositol-1,4,5-trisphosph...

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Autores principales: Hernjak, Nicholas, Slepchenko, Boris M., Fernald, Kathleen, Fink, Charles C., Fortin, Dale, Moraru, Ion I., Watras, James, Loew, Leslie M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2005
Materias:
Biophysical Theory and Modeling
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366947/
https://ncbi.nlm.nih.gov/pubmed/16169982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.065771
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