Rational Design of Anticytoadherence Inhibitors for Plasmodium falciparum Based on the Crystal Structure of Human Intercellular Adhesion Molecule 1

Adhesion of Plasmodium falciparum-infected erythrocytes (IE) to host endothelium has been associated with pathology in malaria. Although the interaction with endothelial cells can be complex due to the relatively large number of host receptors available for binding, specific proteins have been ident...

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Main Authors: Dormeyer, Matthias, Adams, Yvonne, Kramer, Bernd, Chakravorty, Srabasti, Tse, Man Tsuey, Pegoraro, Stefano, Whittaker, Lisa, Lanzer, Michael, Craig, Alister
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2006
Teme:
Mechanisms of Action: Physiological Effects
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366927/
https://ncbi.nlm.nih.gov/pubmed/16436732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.724-730.2006
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