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Effect of Ribavirin and Glucocorticoid Treatment in a Mouse Model of Human Metapneumovirus Infection

Human metapneumovirus (hMPV)-infected BALB/c mice were treated with ribavirin (40 mg/kg of body weight twice a day intraperitoneally), corticosterone (0.2 mg/ml in water), or both modalities. Ribavirin significantly decreased both hMPV replication in lungs (by 5 log(10)) and global pulmonary inflamm...

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Detalhes bibliográficos
Main Authors: Hamelin, Marie-Ève, Prince, Gregory A., Boivin, Guy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366914/
https://ncbi.nlm.nih.gov/pubmed/16436743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.2.774-777.2006
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