A Minimal Chimera of Human Cyclin T1 and Tat Binds TAR and Activates Human Immunodeficiency Virus Transcription in Murine Cells

The transcriptional elongation of human immunodeficiency virus type 1 (HIV-1) is mediated by the virally encoded transactivator Tat and its cellular cofactor, positive transcription elongation factor b (P-TEFb). The human cyclin T1 (hCycT1) subunit of P-TEFb forms a stable complex with Tat and the t...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Fujinaga, Koh, Irwin, Dan, Taube, Ran, Zhang, Fan, Geyer, Matthias, Peterlin, B. Matija
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438619/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.12934-12939.2002
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