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Hypoosmotic Cell Swelling as a Novel Mechanism for Modulation of Cloned HCN2 Channels

This work demonstrates cell swelling as a new regulatory mechanism for the cloned hyperpolarization-activated, cyclic nucleotide-gated channel 2 (HCN2). HCN2 channels were coexpressed with aquaporin1 in Xenopus laevis oocytes and currents were monitored using a two-electrode voltage-clamp. HCN2 chan...

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Detalhes bibliográficos
Main Authors: Calloe, Kirstine, Elmedyb, Pernille, Olesen, Soren-Peter, Jorgensen, Nanna K., Grunnet, Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366717/
https://ncbi.nlm.nih.gov/pubmed/15980171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.063792
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