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Requirement for Vacuolar H(+)-ATPase Activity and Ca(2+) Gradient during Entry of Rotavirus into MA104 Cells

The mechanism by which rotavirus and other nonenveloped viruses enter the cell is still not clear. We have proposed an endocytosis model where the critical step for virus uncoating and membrane permeabilization is the decrease in Ca(2+) concentration in the endosome. In this paper, we monitored rota...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chemello, Maria Elena, Aristimuño, Olga Carolina, Michelangeli, Fabián, Ruiz, Marie-Christine
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC136671/
https://ncbi.nlm.nih.gov/pubmed/12438636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.24.13083-13087.2002
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