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Permeation of Aromatic Carboxylic Acids across Lipid Bilayers: The pH-Partition Hypothesis Revisited

According to the pH-partition hypothesis the charged species of organic compounds do not contribute to lipid bilayer permeation as they generally show negligible partitioning into n-octanol. With this assumption, membrane permeation is related to the molar fraction of the neutral species at a partic...

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Detalhes bibliográficos
Main Authors: Thomae, Anita V., Wunderli-Allenspach, Heidi, Krämer, Stefanie D.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366683/
https://ncbi.nlm.nih.gov/pubmed/15951388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060871
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