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Tissue-Specific Transcriptional Targeting of a Replication-Competent Retroviral Vector

The inability of replication-defective viral vectors to efficiently transduce tumor cells in vivo has prevented the successful application of such vectors in gene therapy of cancer. To address the need for more efficient gene delivery systems, we have developed replication-competent retroviral (RCR)...

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Udgivet i:J Virol
Principais autores: Logg, Christopher R., Logg, Aki, Matusik, Robert J., Bochner, Bernard H., Kasahara, Noriyuki
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Gene Therapy
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136666/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.12783-12791.2002
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