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A cis-Acting Element That Directs Circular Adeno-Associated Virus Replication and Packaging

A novel pathway of adeno-associated virus (AAV) replication marked by the assembly of circular monomer duplex intermediates (cAAV) has been recently discovered. In the present report we identify a single AD domain of the inverted terminal repeat as a minimal origin of cAAV replication. A small inter...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Musatov, Sergei, Roberts, Jill, Pfaff, Donald, Kaplitt, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2002
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136660/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12438604/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.24.12792-12802.2002
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