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Structural Elements in IGP Synthase Exclude Water to Optimize Ammonia Transfer
In the complex pathway of histidine biosynthesis, a key branch point linking amino acid and purine biosynthesis is catalyzed by the bifunctional enzyme imidazole glycerol phosphate (IGP) synthase. The first domain of IGP synthase, a triad glutamine amidotransferase, hydrolyzes glutamine to form glut...
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Principais autores: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Biophysical Society
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366548/ https://ncbi.nlm.nih.gov/pubmed/15849257 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.058651 |
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