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Rigid-Cluster Models of Conformational Transitions in Macromolecular Machines and Assemblies

We present a rigid-body-based technique (called rigid-cluster elastic network interpolation) to generate feasible transition pathways between two distinct conformations of a macromolecular assembly. Many biological molecules and assemblies consist of domains which act more or less as rigid bodies du...

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Bibliografski detalji
Glavni autori: Kim, Moon K., Jernigan, Robert L., Chirikjian, Gregory S.
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2005
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366543/
https://ncbi.nlm.nih.gov/pubmed/15833998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.044347
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