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Solid Phase DNA Amplification: A Brownian Dynamics Study of Crowding Effects
Solid phase amplification (SPA), a new method to amplify DNA, is characterized by the use of surface-bound primers. This limits the amplification to two-dimensional surfaces and therefore allows the easy parallelization of DNA amplification in a single system. SPA leads to the formation of small but...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Biophysical Society
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1366531/ https://ncbi.nlm.nih.gov/pubmed/15821160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051904 |
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