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Solid Phase DNA Amplification: A Brownian Dynamics Study of Crowding Effects

Solid phase amplification (SPA), a new method to amplify DNA, is characterized by the use of surface-bound primers. This limits the amplification to two-dimensional surfaces and therefore allows the easy parallelization of DNA amplification in a single system. SPA leads to the formation of small but...

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Detalhes bibliográficos
Main Authors: Mercier, Jean-François, Slater, Gary W.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366531/
https://ncbi.nlm.nih.gov/pubmed/15821160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.051904
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