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Phosphorylation by the Varicella-Zoster Virus ORF47 Protein Serine Kinase Determines whether Endocytosed Viral gE Traffics to the trans-Golgi Network or Recycles to the Cell Membrane

Like all alphaherpesviruses, varicella-zoster virus (VZV) infection proceeds by both cell-cell spread and virion production. Virions are enveloped within vacuoles located near the trans-Golgi network (TGN), while in cell-cell spread, surface glycoproteins fuse cells into syncytia. In this report, we...

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Detalhes bibliográficos
Main Authors: Kenyon, T. K., Cohen, Jeffrey I., Grose, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136633/
https://ncbi.nlm.nih.gov/pubmed/12368341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10980-10993.2002
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