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Mutations Conferring Resistance to Neutralization by a Soluble Form of the Neurotrophin Receptor (p75NTR) Map outside of the Known Antigenic Sites of the Rabies Virus Glycoprotein

The neurotrophin receptor (p75NTR) serves as a receptor for rabies virus (RV). We expressed and purified a soluble chimera consisting of the p75NTR ectodomain fused to the human immunoglobulin G1 (IgG1) Fc fragment (p75-Fc). Although p75-Fc interacts with RV, the infectivity of RV did not decrease s...

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Detalhes bibliográficos
Main Authors: Langevin, Christelle, Tuffereau, Christine
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136618/
https://ncbi.nlm.nih.gov/pubmed/12368318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10756-10765.2002
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