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Productive Infection of Plasmacytoid Dendritic Cells with Human Immunodeficiency Virus Type 1 Is Triggered by CD40 Ligation

Immature plasmacytoid dendritic cells are the principal alpha interferon-producing cells (IPC), responsible for primary antiviral immunity. IPC express surface molecules CD4, CCR5, and CXCR4, which are known coreceptors required for human immunodeficiency virus (HIV) infection. Here we show that IPC...

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Udgivet i:J Virol
Principais autores: Fong, Lawrence, Mengozzi, Manuela, Abbey, Nancy W., Herndier, Brian G., Engleman, Edgar G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2002
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136607/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368346/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.11033-11041.2002
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