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Recombination of Poliovirus RNA Proceeds in Mixed Replication Complexes Originating from Distinct Replication Start Sites

Genetic recombination occurs frequently during replication of picornaviruses. To explore the intracellular site and structures involved in recombination, HeLa cells were infected with poliovirus type 1 Mahoney and type 2 Sabin. The two genomes were located by fluorescent in situ hybridization and co...

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Detalhes bibliográficos
Main Authors: Egger, Denise, Bienz, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136599/
https://ncbi.nlm.nih.gov/pubmed/12368339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10960-10971.2002
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