Microglia from Creutzfeldt-Jakob Disease-Infected Brains Are Infectious and Show Specific mRNA Activation Profiles

Neurons are often assumed to be the principal sites for replication of the infectious agents causing Creutzfeldt-Jakob disease (CJD), scrapie, and bovine spongiform encephalopathy because they express high levels of normal and pathological prion protein (PrP). However, isolated brain cell types have...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Baker, Christopher A., Martin, Daniel, Manuelidis, Laura
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2002
Gaiak:
Pathogenesis and Immunity
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC136595/
https://ncbi.nlm.nih.gov/pubmed/12368333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.10905-10913.2002
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