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Evidence against a Simple Tethering Model for Enhancement of Herpes Simplex Virus DNA Polymerase Processivity by Accessory Protein UL42

The DNA polymerase holoenzyme of herpes simplex virus type 1 (HSV-1) is a stable heterodimer consisting of a catalytic subunit (Pol) and a processivity factor (UL42). HSV-1 UL42 differs from most DNA polymerase processivity factors in possessing an inherent ability to bind to double-stranded DNA. It...

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Bibliografski detalji
Glavni autori: Chaudhuri, Murari, Parris, Deborah S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2002
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC136589/
https://ncbi.nlm.nih.gov/pubmed/12239303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10270-10281.2002
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