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A Structural Model of Pestivirus E(rns) Based on Disulfide Bond Connectivity and Homology Modeling Reveals an Extremely Rare Vicinal Disulfide

E(rns) is a pestivirus envelope glycoprotein and is the only known viral surface protein with RNase activity. E(rns) is a disulfide-linked homodimer of 100 kDa; it is found on the surface of pestivirus-infected cells and is secreted into the medium. In this study, the disulfide arrangement of the ni...

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Detalhes bibliográficos
Main Authors: Langedijk, J. P. M., van Veelen, P. A., Schaaper, W. M. M., de Ru, A. H., Meloen, R. H., Hulst, M. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136578/
https://ncbi.nlm.nih.gov/pubmed/12239315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10383-10392.2002
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