Exchange of the C-Terminal Part of VP3 from Very Virulent Infectious Bursal Disease Virus Results in an Attenuated Virus with a Unique Antigenic Structure

Infectious bursal disease virus (IBDV) is the major viral pathogen in the poultry industry. Live attenuated serotype 1 vaccine strains are commonly used to protect susceptible chickens during their first 6 weeks of life. Wild-type serotype 1 IBDV strains are highly pathogenic only in chickens, where...

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Detalhes bibliográficos
Main Authors: Boot, Hein J., ter Huurne, A. Agnes H. M., Hoekman, Arjan J. W., Pol, Jan M., Gielkens, Arno L. J., Peeters, Ben P. H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2002
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC136561/
https://ncbi.nlm.nih.gov/pubmed/12239311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.20.10346-10355.2002
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